Zoetis
Zeniquin 100 Tablets
- Tab 1
Zeniquin 100 Tablets
Uses
Dosage & Administration
For the treatment of skin and soft tissue infections in dogs and cats, Zeniquin tablets should be given at a dosage of 2.75 mg/kg once daily for 5 to 14 days.
For the treatment of urinary tract infections in dogs, Zeniquin tablets should be given at a dosage of 2.75 mg/kg once daily for 10 to 14 days.
Efficacy for the treatment of skin and soft tissue infections was confirmed at a dosage of 2.75 mg/kg. In dogs, the dosage may be safely increased to 5.5 mg/kg for two to three days beyond the cessation of clinical signs for a maximum of 30 days, should the patient require more intensive antimicrobial therapy. Some factors to be considered in the determination of dosage are the nature and severity of the infection, the susceptibility of the pathogen, and ability of the patient to combat infection. In dogs and cats, if no improvement is noted within 5 days, the diagnosis should be re-evaluated and a different course of therapy considered. Clinical studies did not reveal improved clinical resolution rates at 5.5 mg/kg in comparison to a dosage of 2.75 mg/kg.
Contraindications & Warnings
Contraindications:
Marbofloxacin and other quinolones have been shown to cause arthropathy in immature animals of most species tested, the dog being particularly sensitive to this side effect. Marbofloxacin is contraindicated in immature dogs during the rapid growth phase (small and medium breeds up to 8 months of age, large breeds up to 12 months of age and giant breeds up to 18 months of age). Marbofloxacin is also contraindicated in cats under 12 months of age. Marbofloxacin is contraindicated in dogs and cats known to be hypersensitive to quinolones.
Cautions:
Quinolones should be used with caution in animals with known or suspected central nervous system (CNS) disorders. In such animals, quinolones have, in rare instances, been associated with CNS stimulation which may lead to convulsive seizures. Quinolones have been shown to produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in immature animals of various species. The use of fluoroquinolones in cats has been reported to adversely affect the retina and such products should be used with caution in cats. Safety in breeding, pregnant or lactating dogs and cats has not been established.
Warnings:
To limit the potential development of antimicrobial resistance: - Fluoroquinolone drugs such as Zeniquin should not be used indiscriminately - Zeniquin should not be used in food producing animals.
Keep out of reach of children.
